Evaluation of anterior chamber angle changes using anterior segment optical coherence tomography in patients with suspected angle closure after YAG laser iridotomy

Purpose: Patients with suspected primary angle closure (PAC) are at higher risk of progressing to PAC and angle-closure glaucoma (ACG). Peripheral laser iridotomy (PLI) is considered an effective measure to increase the opening of the anterior chamber angle. Methods: A prospective cohort study was conducted to evaluate, using anterior segment optical coherence tomography, the changes in anterior chamber angle parameters in patients diagnosed with suspected angle closure who underwent YAG laser PLI. Comparisons were made between pre- and postoperative measurements of angle opening distance (AOD), trabecular–iris space area (TISA), and scleral spur angle (SSA) at 500 μm and 750 μm from the scleral spur. Results: The majority of the patients studied were female ( n = 14, 70%), with a mean age of 57.7 ± 9.4 years. The mean prelaser best-corrected visual acuity was 0.61 ± 0.37, and the mean refraction was + 1.79 ± 1.1 D. The mean intraocular pressure decreased from 18.5 ± 3.09 mmHg preoperatively to 17.6 ± 2.44 mmHg postoperatively, showing a statistically significant difference ( P < 0.05). Significant increases were also observed in AOD 500 and 750 μm, TISA 500 and 750 μm, and SSA following PLI. Conclusion: PLI leads to a significant widening of the anterior chamber angle in patients with suspected angle closure, which may help prevent progression to ACG.