Key result
Spirometry remains the criterion standard and initial diagnostic workup for most patients with respiratory symptoms.
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Spirometry remains first-line for respiratory symptoms; leaves open validation of alternatives in targeted populations.
Chronic respiratory diseases rank among the leading causes of death and disability worldwide, affecting more than half a billion individuals in 2017. This highlights their significant impact on morbidity and mortality.1 Although various diagnostic tests exist, spirometry remains the criterion standard and initial diagnostic workup for most patients with respiratory symptoms.2
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Depta et al. (2025) studied this question. Spirometry remains the criterion standard and initial diagnostic workup for most patients with respiratory symptoms.
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