Key result
Prompt diagnosis and early intervention in a 15-year-old male with sevoflurane-triggered malignant hyperthermia successfully prevented severe complications like acute kidney injury and rhabdomyolysis.
Why the study?
The authors highlight the need for prompt diagnosis and early intervention based on high clinical suspicion to ensure a positive outcome in malignant hyperthermia.
Case Report (n=1)
Prompt diagnosis and early intervention are essential for a positive outcome in malignant hyperthermia.
We report a likely case of malignant hyperthermia triggered by sevoflurane in a 15-year-old male during anesthesia for limb disarticulation surgery. Clinical suspicion was raised with the increasing end-tidal carbon dioxide (ETCO2) and heart rate after induction of general anesthesia. Quick diagnosis, early intervention and teamwork were essential for the positive outcome of this case, preventing the development of more severe complications such as acute kidney injury (AKI) or rhabdomyolysis. Clinical grading score deem this case “greater than likely” despite a negative genetic test. Other metabolic derangements related with the primary neoplasm cannot be excluded but there are no reports on the literature describing such an exuberant reaction. The authors wish to highlight the need of prompt diagnosis, which requires a high degree of suspicion, in order to deliver a positive outcome.
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Moniz et al. (2023) conducted a case report in Malignant Hyperthermia (n=1). Sevoflurane was evaluated on Development of severe complications (acute kidney injury or rhabdomyolysis). Prompt diagnosis and early intervention in a 15-year-old male with sevoflurane-triggered malignant hyperthermia successfully prevented severe complications like acute kidney injury and rhabdomyolysis.
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