Key result
Atrial fibrillation ablation in adults with repaired congenital heart disease is a safe and promising treatment option, with reported success rates ranging from 76% to 84%.
Why the study?
Does atrial fibrillation ablation provide effective and safe outcomes in adults with repaired congenital heart disease?
Does atrial fibrillation ablation provide effective and safe outcomes in adults with repaired congenital heart disease?
Atrial fibrillation ablation, particularly antral isolation of pulmonary veins guided by ICE, appears to be an effective and safe alternative to pharmacological treatment in adults with repaired congenital heart disease.
Answers are grounded in this paper and cite their sources.
May support AF ablation consideration in repaired CHD; leaves open confirmation in larger prospective trials.
The incidence of atrial fibrillation (AF) in congenital heart disease (CHD) adults has increased in the past decades due to a longer life expectancy of this population where the subjects are exposed to cardiac overflow, overpressure and structural changes for years. The literature regarding AF ablation in repaired CHD adults emphasizes the importance of intracardiac echocardiography (ICE) to perform the transseptal puncture and the ablation procedure in the left atrium (LA), both effectively and safely. In small case control studies, where the predominant congenital cardiomyopathy was the atrial septal defect, the most common strategy for ablation was antral isolation of the pulmonary veins showing results, at one year follow-up, similar to those in the general population. The positive results of AF ablation so far, in this specific population, widen the range of therapeutic options for a group of patients whose only chance has been pharmacological treatment, which has proved to be inefficacious in most of the cases and not free from adverse events.
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Aceña et al. (2016) conducted a review in Atrial fibrillation in repaired congenital heart disease. Atrial fibrillation ablation was evaluated. Atrial fibrillation ablation in adults with repaired congenital heart disease is a safe and promising treatment option, with reported success rates ranging from 76% to 84%.
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