A selective system is described that provides a simple and sensitive assay for the detection and analysis of induced mobile element transpositions in Drosophila melanogaster. The system will detect a single event in samples greater than 10(6) and thus provides a eucaryotic assay system for monitoring the induction of transposition by a variety of agents including, but not limited to, chemical carcinogens and toxins, ionizing radiation, and various environmental pollutants. The experimental system focuses on an X-linked rosy+ transposon and a conditional lethal system that permits the detection of a single transposition event in very large samples. The results of a pilot experiment utilizing this system are presented.
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Clark et al. (1985) studied this question.
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