Stereoselective Total Synthesis of (+)‐Norrisolide

In a convergent approach to the marine natural product (+)-norrisolide (1) the two bicyclic ring systems are coupled through the C9C10 bond to assemble the carbon framework in a late stage of the synthesis. Other highlights of the synthetic strategy include the formation of the unusual fused γ-lactone–γ-lactol motif of 1 through a sequence of oxidation reactions.