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Different electrically neutral lipophilic di‐ and triamides were prepared and their ion selectivity in membranes studied. In membranes the ionophore N, N′‐diheptyl‐N, N′‐dimethyl‐succinamide prefers Ca2+ over Mg2+ by a factor of 20 but rejects Na+ and K+ in respect to Mg2+ by a factor of 100 and 10, respectively. This selectivity suffices to perform useful intracellular Mg2+ activity studies.
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Erne et al. (1980) studied this question.
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