Introduction: The leaves of Saraca asoca (the Ashoka tree), a member of Caesalpinioideae family, have been used widely in Traditional medicines; however, their wound healing ability in diabetic condition is not investigated yet. The aim of present study was to investigate the anti-diabetic and wound healing potential of Saraca asoca leaves extract in various streptozocin induces diabetic animal models. Methods: Antidiabetics activity was evaluated in streptozocin induced rat models and wound healing potential was determined using excision and incision wound models. Results: The aqueous and ethanolic extracts induced hypoglycemia and improved glucose tolerance in normal rats, despite the presence of counter-regulatory mechanisms aimed at preventing a decrease in blood glucose levels. This suggests that the hypoglycemic action of the aqueous and ethanolic extracts may be attributed to extra-pancreatic processes or by stimulating the remaining cells to produce more insulin. Conclusion: The present study suggests that the extracts of Saraca asoca leave have significant anti-diabetic and wound healing potential.
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Kumar et al. (2024) studied this question.
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