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July 1, 2002The Journal of Immunology

Overlapping Roles of P-Selectin and α4 Integrin to Recruit Leukocytes to the Central Nervous System in Experimental Autoimmune Encephalomyelitis

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Authors

SKSteven M. KerfootNatural Sciences and Engineering Research CouncilPaul KubesPaul KubesLouisiana State University

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Kerfoot et al. (2002) studied this question.

synapsesocial.com/papers/6a951e5fb7c083589ab2cac1https://doi.org/10.4049/jimmunol.169.2.1000
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The central nervous system environment controls effector CD4+ T cell cytokine profile in experimental allergic encephalomyelitis1997 · 103 citations
  2. 2Molecular Mechanisms Involved in Lymphocyte Recruitment in Inflamed Brain Microvessels: Critical Roles for P-Selectin Glycoprotein Ligand-1 and Heterotrimeric Gi-Linked Receptors2002 · 247 citations
  3. 3α4-integrin-VCAM-1 binding mediates G protein–independent capture of encephalitogenic T cell blasts to CNS white matter microvessels2001 · 353 citations
  4. 4E- and P-Selectin Are Not Involved in the Recruitment of Inflammatory Cells Across the Blood-Brain Barrier in Experimental Autoimmune Encephalomyelitis1997 · 172 citations
  5. 5A Role for Platelets and Endothelial Selectins in Tumor Necrosis Factor-α–Induced Leukocyte Recruitment in the Brain Microvasculature2000 · 238 citations