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October 10, 1995Proceedings of the National Academy of SciencesOpen Access

The nascent-polypeptide-associated complex: having a "NAC" for fidelity in translocation.

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Authors

WWWilliam WicknerDartmouth College

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Implication

In vitro results are preliminary; leaves open translation to clinical cardiovascular practice.

Key Points

Key points are not available for this paper at this time.

Cite This Study

William Wickner (1995) studied this question.

synapsesocial.com/papers/6a952373d002db7cabf58ab0 https://doi.org/10.1073/pnas.92.21.9433

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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

1Purification of a membrane-associated protein complex required for protein translocation across the endoplasmic reticulum.1980 · 512 citations
2An <i>E. coli</i> Ribonucleoprotein Containing 4.5 <i>S</i> RNA Resembles Mammalian Signal Recognition Particle1990 · 286 citations
3The intrinsic ability of ribosomes to bind to endoplasmic reticulum membranes is regulated by signal recognition particle and nascent-polypeptide-associated complex.1995 · 78 citations
4Protein translocation across the endoplasmic reticulum. II. Isolation and characterization of the signal recognition particle receptor.1982 · 479 citations