Why the study?
Does chordal preservation during mitral valve replacement improve long-term left ventricular ejection fraction compared to conventional chordal resection in patients with mitral stenosis?
Does chordal preservation during mitral valve replacement improve long-term left ventricular ejection fraction compared to conventional chordal resection in patients with mitral stenosis?
Preserving the chordae tendineae during mitral valve replacement for mitral stenosis significantly protects long-term left ventricular systolic function compared to conventional chordal resection.
Answers are grounded in this paper and cite their sources.
Chordal preservation was associated with smaller long-term LVEF decline after MVR for MS; hypothesis-generating and requires prospective confirmation.
Carrying out a mitral valve replacement (MVR) while preserving all chordae tendineae in patients with mitral regurgitation has been proven beneficial to the left ventricular performance. To evaluate the effectiveness of this technique in patients with mitral stenosis, a comparison of the echocardiographic data between patients who were operated on using this technique (Group Preservation = GroupP, n = 15), and those operated on using the conventional method of MVR (Group Conventional = GroupC, n = 15) was made. All patients were examined before surgery, 6 months after surgery and 8 years after surgery. The study population was limited to patients who had no evidence of coronary artery disease, aortic stenosis and/or regurgitation and patients who had pure mitral stenosis. Echocardiographic measurements obtained both 6 months and 8 years postoperatively revealed a significant decrease in the left ventricular ejection fraction in GroupC (61.33+/-9.29% preoperatively, 53.2+/-10.3% postoperatively). The difference between the decrease in the left ventricular ejection fraction of the two groups was statistically significant (-0.71+/-6.28% in GroupP, -8.07+/-13.35% in GroupC). There was no evidence of prosthetic valve dysfunction and no operative deaths. Two patients died in GroupP, 3 patients died in GroupC within the 8 year period. The conclusion was reached, that if suitable, mitral valve replacement while preserving the chordae tendineae is expected to have a beneficial effect on postoperative left ventricular performance in patients with mitral stenosis.
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Kayacıoğlu et al. (2003) studied this question.
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