PERSPECfIVES AND SUMMARY 999 DNA SYNTHESIS ON SINGLE-STRANDED CIRCULAR DNA 1001 Priming by RNA Polymerase 1002 Priming by dnaG Protein 1003 Priming by dnaG Protein in Conjunction with Other Proteins 1005 DNA SYNTHESIS ON DOUBLE-STRANDED DNA 1007 DNA Synthesis from a 3'-hydroxyl End at a Strand Break 1007 Processing of Primer RNA and Use of Two Initiation Mechanisms 1010 Activation of the Origin by Transcription 1013 Formation of Nascent Fragments 1017 INITIATION OF REPLICATION OF THE E. COLI CHROMOSOME 1020 Function of Required Gene Products 1020 Detection of the Origin of Replication 1023 REGULATION OF DNA REPLICATION ... 1026 CONCLUSIONS
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Tomizawa et al. (1979) studied this question.