Why the study?
Does intensive hypotensive treatment cause severe complications in patients with uATBAD and unknown carotid occlusion?
Does intensive hypotensive treatment cause severe complications in patients with uATBAD and unknown carotid occlusion?
Intensive hypotensive treatment for uncomplicated acute type B aortic dissection may cause severe complications like cerebral infarct in patients with unknown supra-aortic trunk occlusions, challenging current guidelines.
INTRODUCTION: Despite weak evidence, current treatment guidelines for uncomplicated acute type B aortic dissection (uATBAD) consistently recommend intensive and rapid lowering of systolic blood pressure and heart rate. REPORT: The case of a 62 year old man with uATBAD, who was treated according to guidelines, is presented. Owing to an unknown chronic occlusion of the left carotid artery combined with intensive hypotensive treatment, the patient developed a cerebral infarct. DISCUSSION: The case illustrates a severe complication of the widely accepted management of uATBAD. This case, along with scrutiny of guidelines and the evidence behind these guidelines, provoke questions regarding the rationale of current conservative management, and whether it should be challenged with alternative strategies employing a more cautious blood pressure regimen. It also highlights the importance of evaluating the vessels of the supra-aortic trunk when determining the extent of the dissection.
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Sörelius et al. (2018) studied this question.
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