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Promazine hydrochloride (“Sparine”) is a phenothiazine derivative which has recently been introduced to this country with claims to be a “tranquillizing” drug. It is closely related chemically to chlorpromazine but does not contain the chlorine atom which has been thought to cause the undesirable side effects of the promazine group. The structural formula of Sparine compares with that of chlorpromazine as follows:
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Simpson et al. (1958) studied this question.
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