This case highlights a rare presentation of pulmonary epithelioid hemangioendothelioma with systemic spread including unusual gingival metastasis.
Consider gingival metastasis in progressive pulmonary epithelioid hemangioendothelioma; single-case report extends known spread but leaves practice implications open.
We report a case of a pulmonary epithelioid hemangioendothelioma presenting as a solitary pulmonary nodule with subsequent systemic spread, including histologically documented gingival metastasis. Chest radiography and computed tomography at initial evaluation showed a solitary 2 cm pulmonary nodule, associated with pleural indentation and vascular convergence. The tumor later spread systemically, including multiple pulmonary nodules, bilateral pleural effusions, and gingival swelling and erosion. A biopsy of the gingival lesion showed histologic features identical to that of the lung biopsy.
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Nagata et al. (1999) studied this question.
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