Measuring adrenal function in out-patients using topical corticosteroids

A number of studies describing the effects on pituitary adrenal function of topically applied corticosteroids are reviewed. It is concluded that the adrenal function of the majority of out-patients is little affected by treatment with correctly prescribed topical corticosteroids. However, where patients need brief periods of treatment with large quantities of potent topical corticosteroids for extensive disease, clinicians should be aware of the possibility of transient adrenal suppression.