Cardiac myxomas secrete IL-6 and IL-8, which may play a role in the pathogenesis of acute myocardial infarction in patients with normal coronary arteries.
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May link cardiac myxoma to AMI via IL-6/IL-8; hypothesis-generating case report requiring prospective confirmation.
Three cases of patients with cardiac myxoma who had attacks of acute myocardial infarction are presented. Cineangiographic study showed normal coronary arteries. Immunohistochemical and serologic examination revealed that both interleukin-6 and interleukin-8 were secreted in cardiac myxoma. The authors discuss the relation between these cytokines and myocardial infarction with normal coronary arteries.
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Isobe et al. (1996) studied this question.
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