Why the study?
Does smoking increase postprandial lipemia and atherogenic remnant particles in healthy normolipemic males after a fat-rich meal?
Population
24 healthy normolipemic males with similar fasting lipoprotein profiles, body composition, and lifestyles.
Comparison
Fat-rich mixed meal administered to smokers. vs Fat-rich mixed meal administered to nonsmoking…
Design
Cohort
Follow-up
8 hours
Authors
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Smoking-associated postprandial remnant elevation should not yet change practice; leaves open causal contribution to CAD risk in normolipemic men.
Does smoking increase postprandial lipemia and atherogenic remnant particles in healthy normolipemic males after a fat-rich meal?
Smokers exhibit impaired triglyceride tolerance and defective clearance of chylomicrons and their remnants, suggesting a mechanism for their increased risk of coronary artery disease despite normal fasting lipid profiles.
Mero et al. (1997) studied this question.
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