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August 31, 2026Quality of Life ResearchOpen Access

Measurement properties of a patient-reported outcome scale for peptic ulcer: a validation study using classical test theory and generalizability theory

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Authors

FXFang XuNLNa LuoTFTianLe Fu

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Overview

Validation study demonstrates acceptable psychometric performance of an outcome scale in peptic ulcer disease, highlighting its clinical utility for monitoring recovery.

Key Points

  • To evaluate the reliability, validity, responsiveness, and domain-level measurement precision of the Patient-Reported Outcome Scale for Peptic Ulcer (PROISCD-PU) using Classical Test Theory and Generalizability Theory.
  • Assessed psychometric properties using an integrated framework combining Classical Test Theory (item-domain correlations and structural equation modeling) and Generalizability Theory.
  • Computed absolute dependability coefficients under observed and alternative item configurations separately across individual domains.
  • Internal consistency was acceptable for most domains, with structural equation modeling confirming construct validity, and discriminant validity supported in disease-specific, general module, and spirituality/belief domains.
  • Treatment produced significant improvements across all domains and the total scale, with standardized response mean values indicating moderate to large responsiveness.
  • Generalizability analysis identified person-by-item interaction as the primary variance source, showing acceptable dependability in mental, social, and disease-specific domains, but lower precision in physical and spiritual health.

Cite This Study

Xu et al. (2026) studied this question.

synapsesocial.com/papers/6a954223f20e493292a74433https://doi.org/10.1007/s11136-026-04373-y
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