Key result
Surgical excision of an atrial septal paraganglioma, initially misdiagnosed as a myxoma, led to a favorable recovery with no recurrence over 1 year of follow-up.
Why the study?
Atrial septal paraganglioma shares clinical manifestations and imaging characteristics with myxoma, which can lead to misdiagnosis.
Case Report (n=1)
No
Highlights the importance of accurate diagnosis of cardiac tumors, as rare paragangliomas can mimic myxomas clinically and on imaging.
Answers are grounded in this paper and cite their sources.
Rare atrial paraganglioma may mimic myxoma; case report leaves open reliable preoperative differentiation.
BACKGROUND: Cardiac tumors are relatively uncommon, with myxoma being the most prevalent. Atrial septal paraganglioma is a significantly rarer form of malignant cardiac tumor that secretes catecholamines. There are notable similarities in their clinical manifestations and imaging characteristics, which can lead to misdiagnosis. CASE PRESENTATION: We report a case of a 47-year-old Han man with atypical chest pain and syncope who was found to have a mass (3.6 cm × 2.9 cm) in the left atrium. After an imaging examination, a myxoma was suspected. The tumor was excised during a cardiac surgery, and subsequent pathological analysis determined that the mass was actually a paraganglioma. The patient experienced a favorable recovery, and there was no evidence of recurrence during a 1-year period of postoperative monitoring. CONCLUSION: This case emphasizes the importance of accurate diagnosis of cardiac tumors, especially in atypical clinical manifestations, imaging, and biochemical auxiliary examination. Accurate diagnosis is crucial in the choice of treatment options and prognostic evaluation.
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Yu et al. (2025) conducted a case report in Atrial septal paraganglioma (n=1). Surgical excision was evaluated on Patient recovery and tumor recurrence. Surgical excision of an atrial septal paraganglioma, initially misdiagnosed as a myxoma, led to a favorable recovery with no recurrence over 1 year of follow-up.
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