Key result
Antibiotics and surgical intervention was associated with 31% mortality compared to 60% with antibiotics alone in patients with pericarditis as a presenting sign of infective endocarditis.
Why the study?
Does surgical intervention combined with antibiotics improve survival compared to antibiotics alone in patients presenting with pericarditis as a sign of infective endocarditis?
Does surgical intervention combined with antibiotics improve survival compared to antibiotics alone in patients presenting with pericarditis as a sign of infective endocarditis?
Absolute Event Rate: 31% vs 60%
Infective endocarditis should be considered in patients presenting with pericarditis, and optimal therapy may require both antibiotics and surgical intervention to reduce mortality.
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May support combined antibiotics and surgery in endocarditis presenting as pericarditis; hypothesis-generating and requires prospective confirmation.
Katz et al. (2008) conducted a review in Infective endocarditis presenting as pericarditis (n=21). Antibiotics and surgical intervention vs. Antibiotics alone was evaluated on Mortality. Antibiotics and surgical intervention was associated with 31% mortality compared to 60% with antibiotics alone in patients with pericarditis as a presenting sign of infective endocarditis.
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