Transcriptional Activation of Alpha/Beta Interferon Genes: Interference by Nonsegmented Negative-Strand RNA Viruses

Alpha/beta interferons (IFN-α/β), including the single IFN-β and a large group of IFN-α isotypes, represent an essential element of host defense against viruses and other pathogens, as both IFN-α and IFN-β excite immediate innate antiviral and antiproliferative activities in cells and alert