Single-hole hollow polymer microspheres (see Figure) have been synthesized through the direct polymerization and cross-linking reactions occurring at the surface of carboxyl-capping polystyrene colloids, followed by removal of the core particles. The molecular imprinting of these single-hole hollow microspheres towards the specific high-capacity uptake of target species opens new routes to promising applications.
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Guan et al. (2007) studied this question.
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