Tackling poison and leach: catalysis by dangling thiol–palladium functions within a porous metal–organic solid

Self-standing thiol (-SH) groups within a Zr(IV)-based metal-organic framework (MOF) anchor Pd(II) atoms for catalytic applications: the spatial constraint prevents the thiol groups from sealing off/poisoning the Pd(II) center, while the strong Pd-S bond precludes Pd leaching, enabling multiple cycles of heterogeneous catalysis to be executed.