Thiocyanate and Basal Blood Pressure

Many conflicting views have been published since thio- cyanates were first administered therapeutically at the beginning of this century; and although Hines (1946) and Watkinson and Evans (1947) stated that these are the only drugs capable of satisfactory use in the treatment of hypertensive disease, many are not con- vinced of their action. For example, Ayman (1930, 1931) endeavoured to show that their effect was nm,i not greater than that of placebos, basing his criteria of action mainly on sympto- matic improvement and not so much on pressure changes.