A strain of Enterobacter cloacae resistant to silver sulfadiazine was recovered from a unit in which this antimicrobial agent was in use. This strain was found to harbor an R factor responsible for resistance to carbenicillin, kanamycin and ampicillin. These antibiotic resistances were transferable to Escherichia coli by mating. Resistance to silver sulfadiazine was not, however, transmissible.
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Carr et al. (2009) studied this question.
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