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Fifty convicts of the Missouri State Prison who were between the ages of 21 and 50 volunteered for cervical discography. Three disk spaces were injected in each individual. None had a history of prior neck injury or of neck or arm pain. Extravasation of contrast media (50% sodium diatrizoate [Hypaque Sodium]) occurred at two levels in all cases and in 80% of the remaining spaces. In only 10 disk spaces out of the total of 148 did the sodium diatrizoate remain within the central confines of the annulus in the pattern referred to as "normal" by previous writers. Cervical discography is a painful and expensive procedure and is without diagnostic value.
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Earl P. Holt (1964) studied this question.
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