Highly Efficient One‐Pot Synthesis of 2‐Substituted Quinazolines and 4 H ‐Benzo[ d ][1,3]oxazines via Cross Dehydrogenative Coupling using Sodium Hypochlorite

This communication describes a catalyst‐free synthesis of 2‐substituted quinazolines and 4 H ‐benzo[ d ][1,3]oxazines using commericially available sodium hypochlorite as oxidant. Operational simplicity, mild reaction conditions and the ability to construct structurally diverse 2‐quinazolines and 2‐substituted 4 H ‐benzo[ d ][1,3]oxazines by this method render it to be a practical alternative for the synthesis of these heterocycles.