Key result
Enterovirus 71 isolates in Taiwan (2004-2005) showed divergent phylogeny from previous isolates, with no distinct clusters related to varying degrees of disease severity or clinical manifestations.
Observational
Highlights unusual cases of EV71-associated myocarditis and shifting phylogenetic patterns of the virus in Taiwan between 2004 and 2006.
We report unusual cases of myocarditis caused by enterovirus 71 (EV71) and a declining trend in the incidence of EV71 in Taiwan since 2005. Furthermore, phylogenetic analysis of the 5' untranslated region, VP4, and VP1 genes of EV71 isolates in 2004-2005 revealed a divergent phylogeny from the previous Taiwanese isolates. No obvious phylogenetically distinct clones or clusters were found related to varying degrees of disease severity or clinical manifestations.
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Huang et al. (2008) conducted an observational in Enterovirus 71 (EV71) infection. Enterovirus 71 (EV71) was evaluated on Phylogenetic divergence and disease severity. Enterovirus 71 isolates in Taiwan (2004-2005) showed divergent phylogeny from previous isolates, with no distinct clusters related to varying degrees of disease severity or clinical manifestations.
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