Randomized double-blind trial evaluates topical silicone and onion extract for upper-extremity scars, highlighting noninvasive strategies for hypertrophic scar management.
Background: Wound healing is a process that has three overlapping inflammatory, proliferative, and reconstruction phases. Silicone gel and Contractubex (onion extract gel) are two main topical agents used for the prevention and treatment of hypertrophic scars. This clinical trial study aimed to evaluate the efficacy and safety of onion extract and silicone gel on hypertrophic scars of the upper extremity and compare it to non-treated patients.
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Hassanpour et al. (2020) studied this question.
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