The subcutaneous injection of parathyroid extract into normal and thyroparathyroidectomized rats results in definite increases in the serum citric acid level. Doseresponse data indicate that the rise in serum citrate varies with the dose of the extract, the route of the injection and the period of observation. The level of serum citrate of thyroparathyroidectomized rats was found to be significantly lower than that of normal animals. Increased sensitivity and greater uniformity of response to the injected dose was observed in the operated animals as compared to normal animals.
No takes yet. Share an insight, caveat, or question.
L'Heureux et al. (1953) studied this question.