TreatmentMyasthenic CrisesRandt50 summarizes the treatment of myasthenia gravis, particularly the handling of patients with myasthenic crises. This he describes as an inability to maintain pulmonary ventilation in spite of increasingly large doses of neostigmine, owing to weakness of the respiratory muscles, obstruction of the airway from weakness of the laryngeal or pharyngeal musculature or atelectasis and pneumonia from inability to expel secretions. States of this type may be precipitated or contributed to by overdosage with neostigmine, which is known to have a curarizing effect, with directly opposite results from those desired to maintain life. Randt believes that patients . . .
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Henry R. Viets (1954) studied this question.
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