The Induction of Ovulation in the Squirrel Monkey ( Saimiri Sciureus ) With Pregnant Mares Serum (Pms) and Human Chorionic Gonadotrophin (Hcg)

Successful induction of ovulation in some cyclic adult and prepubertal species of Old World monkey, Macacca mulatta, has been reported by Van Wagenen & Simpson (1957) and by Simpson & Van Wagenen (1962), using injected extracts of monkey pituitaries and human postmenopausal gonadotrophins respectively. In these studies ovulation was determined by histological examination of the ovary and no attempts were made to recover freshly ovulated eggs from the Fallopian tubes. Efforts to induce ovulation by injection of monkey pituitary were unsuccessful. The first experiments are now reported of inducing ovulation, with injections of pregnant mares serum (pms) and human chorionic gonadotrophin (hcg), in a species of New World monkey, Saimiri sciureus, the common squirrel monkey, as a step towards obtaining pregnancies in this species by artificial insemination.