On the Use of Immune Serum at Various Intervals after the Inoculation of Yellow Fever Virus into Rhesus Monkeys

Summary and Conclusions Immune serum from recovered animals, when injected at 24 to 48 hours following inoculation with yellow fever virus, was capable of preventing fever or ameliorating the disease in a significant proportion of experimental monkeys. After forty-eight hours the effect was less definite. In no instance did the serum prevent death when administration was delayed until the temperature of the monkey had reached 104°F.