Estrogens Administration in Female Transsexuals Augmented Delta and Rem Sleep Stages after Six Months of Treatment

The transsexual condition (TS) (Gender Dysphoria DSM-5) people have a marked incongruence between the gender they have been assigned at birth and their experienced/expressed gender. There are variations in brain structures that express reproductive behavior mainly in the hypothalamus. Also, there are sleep differences between non-transsexual female and male. This gender dimorphism in the sleep regulation is due to anatomical changes previously reported in the hypothalamus, which would suggest that it could also find significant differences in sleep architecture in transsexual persons, before and after hormonal treatment with estrogens.