Key result
Anaplastic thyroid cancer with metastatic involvement of the heart resulted in cardiac death in two out of three reported cases.
Case Report (n=3)
Anaplastic thyroid cancer can be a source of cardiac metastasis and a cause of cardiac death, despite the absence of early symptoms.
Alerts clinicians to possible cardiac metastasis in anaplastic thyroid cancer; leaves open questions on screening and management in advanced disease.
BACKGROUND: Clinically evident cardiac metastases from malignant neoplasms are uncommon. The frequency of thyroid metastasis to the heart is very low. To our knowledge, over the last 20 years only a few cases have been reported in the entire literature. Metastatic cardiac involvement occurs most often during the terminal stage. PATIENTS: We present three cases of anaplastic thyroid cancer with metastatic involvement of the heart. RESULTS: Two of the patients died from cardiac problems. The absence of early symptoms makes the clinical diagnosis of metastatic carcinoma difficult. CONCLUSIONS: Anaplastic thyroid cancer is an aggressive cancer with a dismal prognosis. It should be borne in mind as a source of cardiac metastasis and a cause of cardiac death.
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Giuffrida et al. (2001) conducted a case report in Anaplastic thyroid cancer with cardiac metastasis (n=3). Anaplastic thyroid cancer with cardiac metastasis was evaluated on Death from cardiac problems. Anaplastic thyroid cancer with metastatic involvement of the heart resulted in cardiac death in two out of three reported cases.
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