Yet Another Pathogenic Mechanism forEscherichia coliDiarrhea?

Was it not enough to understand three ways that Escherichia coli could cause diarrhea? Esch. coli can acquire the ability to produce enterotoxins that are heat labile or heat stable. Inflammatory colitis is produced by other, invasive Esch. coli. Several lines of evidence, including Ulshen and Rollo's carefully studied case reported in this issue of the Journal, now suggest at least a fourth type of Esch. coli diarrhea — one that is associated with close adherence of the organism to small-bowel mucosa without recognized invasive or enterotoxigenic properties.Recognition that certain Esch. coli can be enteric pathogens began . . .