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September 1, 1985The Journal of Cell Biology

Selective destruction of nerve growth factor receptor-bearing cells in vitro using a hybrid toxin composed of ricin A chain and a monoclonal antibody against the nerve growth factor receptor.

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Authors

PDPeter S. DiStefanoZebra Biologics (United States)JSJohn B. SchweitzerEast Tennessee State UniversityMTMegumi TaniuchiSaga University

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DiStefano et al. (1985) studied this question.

synapsesocial.com/papers/6a95aa7b7432d0c953ffaa27https://doi.org/10.1083/jcb.101.3.1107
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Characterization of the binding properties and retrograde axonal transport of a monoclonal antibody directed against the rat nerve growth factor receptor.1985 · 173 citations
  2. 2A hybrid protein containing the toxic subunit of ricin and the cell-specific subunit of human chorionic gonadotropin. II. Biologic properties.1979 · 69 citations
  3. 3Levels of enzymes of energy metabolism are controlled by activity of cultured rat myotubes1983 · 39 citations
  4. 4Binding of Nerve Growth Factor Receptor in Sympathetic Ganglia1973 · 179 citations
  5. 5An enzymic method for the trace iodination of immunoglobulins and other proteins1969 · 1,406 citations