Key result
IV esmolol for epinephrine-induced tachycardia triggers acute heart failure and cardiac arrest.
Case Report (n=1)
No
Administering beta-blockers to manage epinephrine-induced hypertension and tachycardia can precipitate severe acute heart failure and cardiac arrest due to reduced contractility against a high afterload.
May warrant avoiding beta-blockers after epinephrine infiltration; case report leaves open safer alternatives.
Epinephrine은 수술 중에 국소마취제와 혼합 사용함으로써 혈관수축을 유발하여 국소마취제의 전신적 흡수를 줄이고, 작용시간을 연장시키며, 수술 부위의 출혈을 감소시키기 위 해 널리 사용되고 있다.그러나 이러한 장점 외에 epinephrine 사용으로 인한 심한 고혈압, 심실 빈맥, 심근 경색, 심정지, 급성 폐부종 등의 부작용이 보고된 바 있다
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Lee et al. (2007) conducted a case report in Hypertension and tachycardia induced by local epinephrine infiltration (n=1). Esmolol administration following local epinephrine infiltration was evaluated on Acute heart failure and cardiac arrest. Intravenous esmolol administered to treat hypertension and tachycardia induced by local epinephrine infiltration resulted in severe acute heart failure and cardiac arrest.
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