Synthesis of some pyridylamino‐1,4‐disubstituted phthalazines

Two general procedures involving the condensation of phthalonitrile or 1,3‐diiminoisoindoline with various aminopicolines, followed by ring expansion with hydrazine to the corresponding phthalazine are described. Syntheses are reported of 1, 4‐di(3′‐methyl‐2′‐pyridyl) aminophthalazine, 1,4‐di(5′‐methyl‐2′‐pyridyl)aminophthalazine, and 1,4‐di(4′, 6′‐dimethyl‐2′‐pyridyl)aminophthalazine.