Organ-on-a-Chip Engineered Microenvironments for Safety and Efficacy Testing

The need toimprove testing platforms for current and new pharmaceuticals has helped generate studies involving “organs-on-a-chip” technologies in recent years. This text, aimed at a readership including biomedical engineers, entrepreneurs, design engineers, new drug investigators, etc., attempts to survey the current state of the art in this area of endeavor. It does this well, with 15 chapters from 36 contributors from eight countries. The text covers the many justifications for this work, multiple examples of platforms involving one or more lines of organ cells, discussion of the technologies involved in system design, and one chapter giving an example of a multi-organ-on-a-chip design.