Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles

(Cell Reports 18, 2780–2794; March 14, 2017) In the originally published version of this article, the sample names in Figure 5D were incorrectly ordered during assembly of the heatmap. The sample order has now been corrected online, and the corrected figure appears below. The authors regret this error. Also, due to a misunderstanding prior to publication, the TCGA network authors were not properly indexed in PubMed. This has now been corrected online.Figure 5ARID1A Is Hypermethylated and Has Low Expression in the IDH COCA (original)View Large Image Figure ViewerDownload Hi-res image Download (PPT) Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular ProfilesFarshidfar et al.Cell ReportsMarch 14, 2017In BriefFarshidfar et al. present The Cancer Genome Atlas (TCGA) marker analysis of cholangiocarcinoma. Through multi-platform analyses, they identify a distinct subtype enriched for IDH mutants. This subtype shows increased mitochondrial and decreased chromatin modifier gene expression, including potential epigenetic silencing of ARID1A. Other IDH-mutant liver cancers molecularly resemble cholangiocarcinoma.