Contributions to the Pharmacology and Therapeutics of Iodids

I shall present here a summary of the results of certain studies of the pharmacology and therapeutics of iodids carried on in the Section on Dermatology and Syphilology of the Mayo Clinic during the last two years. Detailed accounts of methods and data covering each phase of the work will be published later. Throughout these studies the method of Kendall1for the determination of iodin has been scrupulously followed. The advantages of this method are numerous, chief among which are its delicacy and accuracy with minute amounts of iodin, and, therefore, its adaptability to small amounts of blood and spinal fluid. ADMINISTRATION BY MOUTH It is well known that small doses of iodids by mouth are rapidly absorbed and eliminated. The recent use of massive doses of iodids has raised the question of whether large doses are absorbed proportionately and, if they are absorbed, whether the iodid is excreted