Somatomedin (SM) was determined by bioassay in cord blood from 100 neonates born at 24-42 weeks of gestation and from three infants with major congenital malformations. SM levels rose with gestational age and had a positive correlation with birth weight, length and head circumference independantly of gestational age. These findings suggest a relationship between somatomedin and fetal growth.
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Gluckman et al. (1976) studied this question.
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