Evolutionary trace report_maker: a new type of service for comparative analysis of proteins

Summary: Evolutionary trace report_maker offers a new type of service for researchers investigating the function of novel proteins. It pools, from different sources, information about protein sequence, structure and elementary annotation, and to that background superimposes inference about the evolutionary behavior of individual residues, using real-valued evolutionary trace method. As its only input it takes a Protein Data Bank identifier or UniProt accession number, and returns a human-readable document in PDF format, supplemented by the original data needed to reproduce the results quoted in the report. Availability: Evolutionary trace reports are freely available for academic users at Contact: {imihalek,ires,lichtarge}@bcm.tmc.edu