Pachyonychia congenita and steatocystoma multiplex

Pachyonychia congenita and steatocystoma multiplex are each rare conditions. It is still not widely appreciated that they are both manifestations of the same autosomal gene. Extensive clinical, X‐ray and laboratory investigations on two affected members of a family, in which three generations are known to be affected, failed to reveal any specific abnormality other than the skin and nail lesions.