Key result
Obesity was significantly associated with hypercholesterolemia in males (41.7% vs 0% in normal weight, p<0.001) and elevated systolic blood pressure in females (50% vs 0%, p=0.001).
Why the study?
Does overweight/obesity increase the prevalence of cardiovascular risk factors (dyslipidemia, hypertension, inflammation) differently in adult Sudanese males and females?
Cross-Sectional (n=158)
Does overweight/obesity increase the prevalence of cardiovascular risk factors (dyslipidemia, hypertension, inflammation) differently in adult Sudanese males and females?
Obesity in Sudanese adults exhibits a sex-specific cardiovascular risk profile, with males predominantly developing dyslipidemia and females predominantly developing hypertension and systemic inflammation.
Supports sex-specific CV risk assessment in obese Sudanese adults; hypothesis-generating and requires longitudinal confirmation before practice change.
Subjects and methods: In this study, the effect of obesity on the development of dyslipidemia, hypertension and glucose intolerance among Sudanese adults attending weight reduction programs was investigated. According to the BMI (Body mass index), 98 overweight/obese and 60 normal weight adults were included. Anthropometric measures were taken, lipid profile and C – reactive protein (CRP) were determined using commercial kits.Results: Obesity related dyslipidemia seems to affect overweight/obese males more than females. On the other hand, overweight /obesity among females, not like males, was found to be associated with high blood pressure probably due inflammation, as determined by CRP level.Conclusion and recommendation: Obesity related dyslipidemia is more prominent among males while obesity related hypertension is a phenomenon among females probably due to release of CRP. We recommend a more detailed study of inflammatory cytokines, in relation to obesity, that mayreflect the mass and/or activity of the adipose tissue.
No takes yet. Share an insight, caveat, or question.
Ahmad et al. (2011) conducted a cross-sectional in Obesity and cardiovascular disease risk factors (n=158). Overweight and obesity vs. Normal weight was evaluated on Total cholesterol ≥200 mg/dl in males (p=<0.001). Obesity was significantly associated with hypercholesterolemia in males (41.7% vs 0% in normal weight, p<0.001) and elevated systolic blood pressure in females (50% vs 0%, p=0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: