3-Aryl-2-cyanoacrylonitriles ( 1a , b ) reacted with 6-aminothiouracil, 2-ethoxy carbonylmethyl-4-oxo-Δ2-thiazoline, 2-cyanomethyl-4-oxo-Δ2-thiazoline and indan-2-one to give pyrido[2,3-d]pyrimidines, thiazolo[3,2-a]pyridines, pyrano [2,3-b]benzopyrrole and pyrido[2,3-b]benzopyrrole, respectively. The IR, MS and 1H-NMR of the synthesized compounds were discussed. The antimicrobial activity of some of the synthesized compounds was tested.
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Mahmoud et al. (2007) studied this question.
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