Key result
Hypertension, diabetes mellitus, and glycated hemoglobin ≥5.7% were significantly associated with increased arterial stiffness, with hypertension increasing the odds of elevated pulse wave velocity by 2.7 times.
Why the study?
Studies have shown a correlation between diabetes and arterial stiffness, motivating an investigation into laboratory and clinical predictors associated with arterial stiffness validated by pulse wave velocity.
Cross-Sectional (n=1,197)
No
Diabetes mellitus, hypertension, and elevated HbA1c are significant independent predictors of increased arterial stiffness as measured by pulse wave velocity.
Elevated PWV should not yet alter management in hypertension or diabetes; leaves open its added value for risk stratification.
Studies in a healthy and diabetic population have shown that there is a correlation between the disease and arterial stiffness, and consequently an increase in Pulse Wave Velocity (PWV). We investigate predictors laboratory and clinical associated with arterial stiffness, validated by the increase in PWV. Our findings showed that the predictor for diabetes mellitus, hypertension, glycated hemoglobin ≥5.7, confirmed the significant association for increased arterial stiffness, validated by the increase in PWV.
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Regla et al. (2022) conducted a cross-sectional in Arterial stiffness (n=1,197). Hypertension, Diabetes Mellitus, and elevated HbA1c vs. Patients without these conditions or with normal HbA1c levels was evaluated on Pulse wave velocity (PWV) ≥ 10 m/s (OR 2.7, 95% CI 1.9-3.9, p=<0.001). Hypertension, diabetes mellitus, and glycated hemoglobin ≥5.7% were significantly associated with increased arterial stiffness, with hypertension increasing the odds of elevated pulse wave velocity by 2.7 times.
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