Key result
Recurrence of takotsubo cardiomyopathy occurred in 6.1% of patients and was associated with higher rates of arterial hypertension and pulmonary disease, but similar long-term mortality compared to non-recurrent cases.
Cohort (n=114)
No
Recurrence of takotsubo cardiomyopathy occurs in approximately 6% of patients and is associated with higher rates of arterial hypertension and pulmonary disease.
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May inform risk stratification for takotsubo recurrence; leaves open need for prospective studies before guiding prevention.
BACKGROUND: Recurrence of takotsubo cardiomyopathy (TTC) is a well-known complication. However, current literature lists only a few isolated cases. We aimed to determine the incidence and clinical significance of recurrent TTC. METHODS & Clinical events like right ventricular involvement, TTC related complications such as life-threatening arrhythmias, pulmonary congestion and in hospital death were observed more frequently in the recurrent episode. Over a mean follow-up of one year the mortality rate was similar in both groups. CONCLUSIONS: Recurrence of TTC within six years after index event is not an uncommon phenomenon. In the event of right ventricular involvement in the relapse phase, it might be associated with a higher complication rate. TTC recurrence should be the first differential diagnosis in patients with a past history of TTC.
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El‐Battrawy et al. (2016) conducted a cohort in Takotsubo cardiomyopathy (n=114). Recurrent takotsubo cardiomyopathy vs. Non-recurrent takotsubo cardiomyopathy was evaluated on Recurrence of takotsubo cardiomyopathy. Recurrence of takotsubo cardiomyopathy occurred in 6.1% of patients and was associated with higher rates of arterial hypertension and pulmonary disease, but similar long-term mortality compared to non-recurrent cases.
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